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Product Name
Recombinant HID1 protein (His tag)
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Description
Recombinant Human HID1 Protein Fragment (677-788) - A high-quality, soluble protein fragment derived from the HID1 protein (Down-regulated in multiple cancers 1), specifically designed for structural and biochemical research applications. This 112-amino acid fragment represents a stable, well-folded region ideal for investigating protein function and interactions.
The full-length HID1 protein (HID1 domain-containing protein) plays an important role in cancer development across multiple tissue types, as evidenced by its down-regulation in various cancers. This protein exhibits dynamic subcellular localization, primarily found in the cytoplasm and associated with Golgi apparatus membranes through lipid anchoring. HID1 demonstrates a unique shuttling behavior between the cytosol and Golgi apparatus, suggesting its involvement in intracellular trafficking and signaling pathways relevant to oncogenesis. The protein's regulatory functions make it a significant target for cancer biology research and therapeutic development.
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Protein name
Protein HID1
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Uniprot ID
Q8IV36
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Gene Name
HID1; C17orf28; DMC1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 677-788 aa (Q8IV36) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 14.84 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 15 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"