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  • hFSH-β-(33-53) peptide

hFSH-β-(33-53) peptide

Not For Human Use, Lab Use Only.

Cat.#: 319781

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    hFSH-β-(33-53) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-YTRDLVYKDPARPKIQKTCTF-OH
  • Sequence
    H-Tyr-Thr-Arg-Asp-Leu-Val-Tyr-Lys-Asp-Pro-Ala-Arg-Pro-Lys-Ile-Gln-Lys-Thr-Cys-Thr-Phe-OH
  • Length (aa)
    21
  • Peptide Purity (HPLC)
    95.3%
  • Molecular Formula
    C115H183N31O32S
  • Molecular Weight
    2543.92
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The hFSH-β-(33-53) peptide is a synthetic fragment derived from the human follicle-stimulating hormone (hFSH) β-subunit. This peptide contains a free sulfhydryl group at Cys-51 but lacks the sequence similarity to the thioredoxin active center, which is present in other regions of the hFSH-β-subunit. Unlike hFSH-β-(81-95), which exhibits thioredoxin-like activity, hFSH-β-(33-53) does not demonstrate catalytic activity in reactivating reduced and denatured ribonuclease (RNase). The peptide corresponds to a receptor-binding domain of the hFSH-β-subunit, though its functional role remains distinct from redox-active regions.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Grasso P, Santa-Coloma TA, Boniface JJ, Reichert LE Jr. A synthetic peptide corresponding to hFSH-beta-(81-95) has thioredoxin-like activity. Mol Cell Endocrinol. 1991 Jul;78(3):163-70. doi: 10.1016/0303-7207(91)90119-d. PMID: 1778302.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"