heteroclitic BCMA72-80 peptide
Not For Human Use, Lab Use Only.
Cat.#: 319266
Special Price 94.20 USD
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Product Name
heteroclitic BCMA72-80 peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
H-YLMFLLRKI-OH
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Sequence
H-Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile-OH
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Length (aa)
9
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Peptide Purity (HPLC)
95.89%
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Molecular Formula
C59H97N13O11S
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Molecular Weight
1196.54
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Source
Synthetic
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Form
Powder
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Description
Heteroclitic BCMA72-80 [YLMFLLRKI] peptide is derived from human BCMA protein. It has a strong HLA-A2 binding affinity and stability with improved immunogenicity from its native BCMA72-80 [VLMFLLRKI] peptide and induces robust BCMA-specific memory CD8+ CTL responses against MM cells.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- Bae J, Parayath N, Ma W, Amiji M, Munshi N, Anderson KC. BCMA peptide-engineered nanoparticles enhance induction and function of antigen-specific CD8+ cytotoxic T lymphocytes against multiple myeloma: clinical applications. Leukemia. 2020 Jan;34(1):210-223. doi: 10.1038/s41375-019-0540-7. Epub 2019 Aug 19. Erratum in: Leukemia. 2020 Jan 16;: PMID: 31427721; PMCID: PMC7297141.
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"