HAVDI peptide

HAVDI peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

Fmoc-HAVDI-OH

Fmoc-His-Ala-Val-Asp-Ile-OH

5

99.46%

C₃₉H₄₉N₇O₁₀

775.84

Synthetic

Powder

The HAVDI peptide is a synthetic sequence that mimics the N-cadherin protein. It can self-assemble into nanofibrous hydrogels that closely resemble the natural extracellular matrix (ECM), providing mechanical support and guiding cell adhesion and proliferation. These bioactive scaffolds are particularly promising in tissue engineering, as they effectively support the growth of both neural and non-neural cell lines.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Kaur H, Roy S. Designing aromatic N-cadherin mimetic short-peptide-based bioactive scaffolds for controlling cellular behaviour. J Mater Chem B. 2021 Aug 7;9(29):5898-5913. doi: 10.1039/d1tb00598g. Epub 2021 Jul 15. PMID: 34263278.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.