H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH peptide

H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

YCFAWKTFC(Disulfide bond)

H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH(Disulfide bond)

9

97.7%

C₅₇H₇₁N₁₁O₁₂S₂

Synthetic

Powder

Selective somatostatin receptor subtype sst4 agonist. In competitive radioligand displacement experiments using the non-selective radioligand ([125I]-(Leu8,D-Trp22,Tyr25)-Somatostatin-28, this peptide exhibited a high affinity for sst4 with an IC50 value of 2.0 ± 0.5 nM. IC50 values for sst1, sst2, sst3, and sst5 were >1000 nM, 622 ± 85 nM, 624 ± 213 nM, and 692 ± 1

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• J.Erchegyi et al., J. Med. Chem., 46, 5597 (2003)

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.