GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat) peptide
Not For Human Use, Lab Use Only.
Cat.#: 301660
Special Price 273.80 USD
-
Product Name
GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat) peptide
-
Documents
Batch to batch variation of the purity
-
Sequence Shortening
EGTFTSDVSSYLEGQAAKEFIAWLVKGR
-
Sequence
H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
-
Length (aa)
28
-
Peptide Purity (HPLC)
95.5%
-
Molecular Formula
C140H214N36O43
-
Molecular Weight
3089.46
-
Source
Synthetic
-
Form
Powder
-
Description
Glucagon-like peptide-1 (GLP-1) is efficiently degraded by the enzyme dipeptidyl peptidase IV (DPP IV), yielding the major metabolite GLP-1 (9-36) amide. GLP-1 (9-36) amide does not affect glucose disposal in mice either in the presence or absence of intact GLP-1 receptors or in the presence or absence of stimulated insulin levels. This suggests that the GLP-1metabolite is not involved in the regulation of glucose homeostasis. Elahi et al. have shown that this GLP-1 metabolite acts as a weak ins
-
Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
-
References
- B.Ahren et al., Diabetes Care, 25, 869 (2002)
- C.F.Deacon et al., Am. J. Physiol. Endocrinol. Metab., 282, E873 (2002)
- B.Rolin et al., Eur. J. Pharmacol., 494, 283 (2004)
- D.Elahi et al., Obesity, 16, 1501 (2008)
-
About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
-
Molar Concentration Calculator
-
Dilution Calculator
-
Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Peptide Property
- Analysed Sequence:A
- Chemical Formula:A
- Sequence length:A
- Extinction coefficient:A M-1cm-1
- GRAVY:A
- Mw average:A
- Theoretical pI:A
- Data Source:Peptide Property Calculator
GRAVY = grand average of hydropathy
X: Hydrophobic uncharged residues, like F I L M V W A and P
X: Basic residues, like R K H
X: Acidic residues, like D E
X: Polar uncharged residues, like G S T C N Q and Y
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"