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  • GLP-1(7-37)(Chiken) / Glucagon-like peptide 1(Gallus gallus)

GLP-1(7-37)(Chiken) / Glucagon-like peptide 1(Gallus gallus)

Not For Human Use, Lab Use Only.

Cat.#: 319892

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    GLP-1(7-37)(Chiken) / Glucagon-like peptide 1(Gallus gallus)
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    HAEGTYTSDITSYLEGQAAKEFIAWLVNGR-NH2
  • Sequence
    His-Ala-Glu-Gly-Thr-Tyr-Thr-Ser-Asp-Ile-Thr-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Asn-Gly-Arg-NH2
  • Length (aa)
    30
  • Peptide Purity (HPLC)
    95.7%
  • Molecular Formula
    C149H224N40O47
  • Molecular Weight
    3327.66
  • Source
    Synthetic
  • Form
    Powder
  • Description

    GLP-1(7-37) is a peptide derived from the tissue-specific processing of proglucagon in the intestine and brain of chickens. The chicken proglucagon gene expresses multiple mRNA transcripts, and in the brain and gut, proglucagon B is cleaved by PC2 to generate glicentin, oxyntomodulin, GLP-1 and GLP-2. The amino acid sequence of glucagon is highly conserved between mammals and chickens, whereas that of GLP-2 is not, suggesting that glucagon-related peptides may play different physiological roles among vertebrates.

    In chickens, GLP-1 functions as an anorexigenic peptide in the central nervous system. GLP-1-immunoreactive perikarya are found in the nucleus tractus solitarii, and proglucagon mRNA levels in the brainstem or medulla oblongata decrease after 24 hours of fasting. Chicken GLP1R is highly expressed in the telencephalon, midbrain, hindbrain and hypothalamus. Both the N- and C-terminal regions of GLP-1 may have important roles for the regulation of food intake in chickens.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Honda K. Glucagon-related peptides and the regulation of food intake in chickens. Anim Sci J. 2016 Sep;87(9):1090-8. doi: 10.1111/asj.12619. Epub 2016 May 6. PMID: 27150835; PMCID: PMC5084811.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"