(Gln53)-Connexin 37 (51-58) (human, mouse, rat) peptide
Not For Human Use, Lab Use Only.
Cat.#: 311404
Special Price 101.20 USD
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Product Name
(Gln53)-Connexin 37 (51-58) (human, mouse, rat) peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
FEQNTAQP
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Sequence
H-Phe-Glu-Gln-Asn-Thr-Ala-Gln-Pro-OH
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Length (aa)
8
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Peptide Purity (HPLC)
96.6%
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Molecular Formula
C40H59N11O15
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Molecular Weight
933.97
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Source
Synthetic
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Form
Powder
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Description
MUT 1, a tumor-associated antigen peptide originally isolated from the mouse Lewis lung carcinoma, appears to be a fragment of the gap junction protein connexin 37, mutated at position 54. MUT 1 induces effective antitumor cytotoxic T lymphocytes and mediates protection against metastasis, as well as rejection of established metastasis. This is the first description of peptide vaccine efficacity in treatment of residual tumors.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- O.Mandelboim et al., Nature, 369, 67 (1994)
- O.Mandelboim et al., Nat. Med., 1, 1179 (1995)
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Peptide Property
- Analysed Sequence:H-FEQNTAQP-OH
- Chemical Formula:C40H59N11O15
- Sequence length:8
- Extinction coefficient:0 M-1cm-1
- GRAVY:-1.46
- Mw average:933.96
- Theoretical pI:3.28
- Data Source:Peptide Property Calculator
GRAVY = grand average of hydropathy
X: Hydrophobic uncharged residues, like F I L M V W A and P
X: Basic residues, like R K H
X: Acidic residues, like D E
X: Polar uncharged residues, like G S T C N Q and Y
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"