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Product Name
Recombinant GKN2 protein (His tag)
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Description
Our recombinant Gastrokine-2 (GKN2) fragment (amino acids 21-184) is a high-purity protein designed to encompass the full BRICHOS functional domain. This product serves as an essential tool for researchers investigating domain-specific functions, particularly in studies related to gastric cancer and cellular regulation.
Gastrokine-2, also known as Blottin, is a human protein that has been identified as down-regulated in gastric cancer, suggesting potential roles in tumor suppression or gastric mucosal protection. As a secreted protein, Gastrokine-2 functions in extracellular environments, where it may participate in cell signaling, tissue maintenance, or protective mechanisms within the gastrointestinal tract. The BRICHOS domain contained within this recombinant fragment is associated with diverse biological activities, including chaperone functions and involvement in protein folding pathways, making this protein valuable for exploring molecular mechanisms in both normal physiology and disease states.
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Protein name
Gastrokine-2
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Uniprot ID
Q86XP6
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Gene Name
GKN2; BLOT; GDDR; TFIZ1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 21-184 aa (Q86XP6) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 19.97 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 20 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"