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Recombinant GHRHR protein (His tag)

Recombinant GHRHR protein (His tag)

Cat.#: 544829

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Special Price 294.7 USD

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Product Information

  • Product Name
    Recombinant GHRHR protein (His tag)
  • Documents
  • Description

    Introducing the recombinant human Growth Hormone-Releasing Hormone Receptor (GHRHR) fragment (residues 23-130), a stable and soluble protein unit designed for structural and biochemical research. This 108-amino acid fragment enables targeted investigation of GHRHR's role in growth hormone regulation, offering researchers a reliable tool for advancing studies in endocrinology and receptor signaling.

    The full-length GHRHR is a G protein-coupled receptor located in the cell membrane that binds growth hormone-releasing factor (GRF). Upon activation, it stimulates adenylyl cyclase through G protein coupling, leading to increased growth hormone secretion, enhanced growth hormone gene transcription, and promotion of somatotroph cell growth. As a multi-pass membrane protein, GHRHR plays a critical role in the hypothalamic-pituitary axis, making it essential for understanding growth regulation and potential therapeutic interventions for growth disorders.

  • Protein name
    Growth hormone-releasing hormone receptor
  • Uniprot ID
    Q02643
  • Gene Name
    GHRHR
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 23-130 aa (Q02643) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 13.59 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 14 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"