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  • GFLG peptide

GFLG peptide

Not For Human Use, Lab Use Only.

Cat.#: 319749

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* Buy 1 get 1 free (?) What is TFA?

Special Price 101.70 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    GFLG peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-GFLG-OH
  • Sequence
    H-Gly-Phe-Leu-Gly-OH
  • Length (aa)
    4
  • Peptide Purity (HPLC)
    95.37%
  • Molecular Formula
    C19H28N4O5
  • Molecular Weight
    392.45
  • Source
    Synthetic
  • Form
    Powder
  • Description
    GLFG oligopeptides exhibit specific sensitivity towards the enzyme cathepsin B, enabling effective controlled release of cargo molecules in the cytoplasm. It serves as an enzyme-cleavable linker in drug delivery systems.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Song SJ, Choi JS. Enzyme-Responsive Amphiphilic Peptide Nanoparticles for Biocompatible and Efficient Drug Delivery. Pharmaceutics. 2022 Jan 7;14(1):143. doi: 10.3390/pharmaceutics14010143. PMID: 35057039; PMCID: PMC8779831.
    • Zhang C, Pan D, Li J, Hu J, Bains A, Guys N, Zhu H, Li X, Luo K, Gong Q, Gu Z. Enzyme-responsive peptide dendrimer-gemcitabine conjugate as a controlled-release drug delivery vehicle with enhanced antitumor efficacy. Acta Biomater. 2017 Jun;55:153-162. doi: 10.1016/j.actbio.2017.02.047. Epub 2017 Mar 2. PMID: 28259838.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"