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Product Name
Recombinant GBG11 protein (His tag)
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Description
Recombinant Human GNG11 Protein Fragment (1-70) is a high-quality, soluble protein fragment derived from the Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11. This fragment is engineered for stability and solubility, making it ideal for structural studies, biochemical assays, and signaling pathway research.
Guanine nucleotide-binding proteins (G proteins) act as modulators or transducers in transmembrane signaling systems. The GNG11 protein, along with its beta and gamma chains, is essential for GTPase activity, GDP-to-GTP exchange, and interactions with effector molecules. It is localized to the cell membrane, anchored to lipids on the cytoplasmic side, playing a critical role in intracellular signal transduction pathways.
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Protein name
Guanine nucleotide-binding protein G
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Uniprot ID
P61952
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Gene Name
GNG11; GNGT11
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-70 aa (P61952) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 9.83 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 12 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"