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Product Name
Recombinant GATA2 protein (His tag)
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Description
Recombinant Human Endothelial Transcription Factor GATA-2 (GATA-binding protein 2) Fragment (aa 292-400) is a high-purity protein designed for structural and biochemical studies. This 109-amino acid fragment, derived from the human GATA2 gene, represents a stable and soluble unit ideal for investigating transcriptional regulation mechanisms in endothelial cells.
Endothelial transcription factor GATA-2 (GATA-binding protein 2) is a transcriptional activator that plays a critical role in regulating endothelin-1 gene expression in endothelial cells. The protein functions by binding to the consensus DNA sequence 5'-AGATAG-3', thereby modulating gene expression in vascular biology. GATA-2 is localized to the nucleus, where it exerts its transcriptional regulatory functions. The full-length protein, encoded by the GATA2 gene (UniProt ID: P23769), is essential for normal endothelial cell function and vascular development.
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Protein name
Endothelial transcription factor GATA-2
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Uniprot ID
P23769
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Gene Name
GATA2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 292-400 aa (P23769) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 13.92 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 14 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"