gamma-glutamyl-cysteinyl-alanine peptide

gamma-glutamyl-cysteinyl-alanine peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-ECA-OH

H-Glu-Cys-Ala-OH

3

95.48%

C₁₁H₁₉N₃O₆S

321.35

Synthetic

Powder

gamma-glutamyl-cysteinyl-alanine was found in kidney bean (Phaseolus vulgaris).
Addition of a nearly tasteless aqueous extract isolated from beans (Phaseolus vulgaris L.) to a model chicken broth enhanced its mouthfulness and complexity and induced a much more long-lasting savory taste sensation on the tongue. gamma-glutamyl-cysteinyl-alanine is one of the key molecules inducing this taste-modifying effect.
Sensory analysis of aqueous solutions showed threshold concentrations between 3.3 and 9.4 mmol/L for an unspecific, slightly astringent sensation. And when added to a savory matrix such as sodium chloride and monosodium glutamate solutions or chicken broth, the detection thresholds of gamma-glutamyl-cysteinyl-alanine decreased significantly and remarkably enhanced mouthfulness, complexity, and long-lastingness of the savory taste were observed.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Dunkel A, Köster J, Hofmann T. Molecular and sensory characterization of gamma-glutamyl peptides as key contributors to the kokumi taste of edible beans (Phaseolus vulgaris L.). J Agric Food Chem. 2007 Aug 8;55(16):6712-9.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.