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Product Name
Recombinant FRMD3 protein (His tag)
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Description
Recombinant Human FRMD3 (FERM domain-containing protein 3) Fragment (aa 31-359) - A high-purity protein fragment specifically designed for studying the complete FERM domain functionality. This product provides researchers with a targeted tool to investigate the tumor suppressor properties and membrane-associated functions of this important protein implicated in lung cancer progression.
FERM domain-containing protein 3 (FRMD3), also known as Band 4.1-like protein 4O, functions as a putative tumor suppressor gene with implications in the origin and progression of lung cancer. The protein localizes to the membrane as a single-pass membrane protein, suggesting its involvement in membrane-associated signaling pathways and cellular organization. As a member of the 4.1 protein family, FRMD3 shares structural homology with other cytoskeletal-associated proteins that regulate cell shape, adhesion, and motility. The tumor suppressor function identified through research (PubMed:17260017) positions FRMD3 as a protein of significant interest in cancer biology and therapeutic development.
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Protein name
FERM domain-containing protein 3
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Uniprot ID
A2A2Y4
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Gene Name
FRMD3; EPB41L4O
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 31-359 aa (A2A2Y4) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 39.96 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 40 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"