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catalog peptide: FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa

FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa

Cat.#: 318734

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Description
FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa
Quantity/Unit 1 Vial
Sequence AMMRF-NH2, AVFRM-NH2, SVFRL-NH2
Length 5
Peptide Purity (%) 95.8%
Molecular Formula C28H47N9O5S2
Molecular Weight 653.86
Source Synthetic
Additional Information All three peptides encoded by the flp-20 gene (AMMRFa, AVFRMa, SVFRLa) were able to activate FRPR-3 receptor, the FMRFamide-like peptide GPCR FRPR-3, with EC50 values in the low nanomolar range. AMMRFa refers to AMMRF-NH2(C28H47N9O5S2, MW: 653.86); AVFRMa = AVFRM-NH2(C28H47N9O5S, MW: 621.79); SVFRLa = SVFRL-NH2(C29H49N9O6, MW: 619.75). These FLP-20 peptides function as an afferent arousal signal that conveys mechanosensory information to central neurons that modulate arousal and other behavioral states.
Storage Guidelines Ideally FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa should be stored in a freezer at or below -9C. FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
Terms Please do not use the peptide for human consumption. NovoPro will immediately deny any order that we feel will be used outside of the scope of its intended purpose.
References

Chew et al., An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans, Neuron (2018), https://doi.org/10.1016/j.neuron.2018.08.003

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