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  • FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa

FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa

Cat.#: 318734

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Product Information

  • Product Name
    FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    AMMRF-NH2, AVFRM-NH2, SVFRL-NH2
  • Length (aa)
    5
  • Peptide Purity (HPLC)
    95.8%
  • Molecular Formula
    C28H47N9O5S2
  • Molecular Weight
    653.86
  • Source
    Synthetic
  • Additional Information
    All three peptides encoded by the flp-20 gene (AMMRFa, AVFRMa, SVFRLa) were able to activate FRPR-3 receptor, the FMRFamide-like peptide GPCR FRPR-3, with EC50 values in the low nanomolar range. AMMRFa refers to AMMRF-NH2(C28H47N9O5S2, MW: 653.86); AVFRMa = AVFRM-NH2(C28H47N9O5S, MW: 621.79); SVFRLa = SVFRL-NH2(C29H49N9O6, MW: 619.75). These FLP-20 peptides function as an afferent arousal signal that conveys mechanosensory information to central neurons that modulate arousal and other behavioral states.
  • Storage Guidelines
    Ideally FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa should be stored in a freezer at or below -9C. FLP-20 neuropeptides:AMMRFa, AVFRMa, SVFRLa should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Chew et al., An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans, Neuron (2018), https://doi.org/10.1016/j.neuron.2018.08.003

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"