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Product Name
Recombinant FLI1 protein (His tag)
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Description
Recombinant Human FLI1 Transcription Factor Fragment (aa 260-370) is a high-purity, stable protein designed for structural and biochemical studies. This 111-amino acid fragment of the Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) offers a soluble and functional unit ideal for investigating transcriptional regulation mechanisms.
The full-length FLI1 protein (UniProt ID: Q01543) is a sequence-specific transcriptional activator in humans that recognizes the DNA motif 5'-C[CA]GGAAGT-3'. It functions as a key regulator in gene expression processes and has been implicated in proto-oncogenic activities. FLI1 localizes to the nucleus, where it exerts its transcriptional control functions. The selected fragment (amino acids 260-370) represents a computationally optimized region that maintains structural integrity while providing a tractable system for experimental analysis of FLI1's biological roles.
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Protein name
Friend leukemia integration 1 transcription factor
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Uniprot ID
Q01543
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Gene Name
FLI1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 260-370 aa (Q01543) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 14.46 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 14 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"