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Recombinant FGF21 protein (His tag)

Recombinant FGF21 protein (His tag)

Cat.#: 546058

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Special Price 294.7 USD

Availability: 3-4 weeks
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Product Information

  • Product Name
    Recombinant FGF21 protein (His tag)
  • Documents
  • Description

    Introducing the recombinant Fibroblast growth factor 21 (FGF-21) fragment (residues 44-209), a highly stable and soluble protein unit designed for structural and biochemical studies. This fragment supports research into glucose metabolism regulation and insulin sensitivity mechanisms.

    Fibroblast growth factor 21 (FGF-21), encoded by the FGF21 gene in Homo sapiens, stimulates glucose uptake in adipocytes by inducing SLC2A1/GLUT1 glucose transporter expression. Its activity is dependent on KLB and plays a critical role in regulating systemic glucose homeostasis and insulin sensitivity. As a secreted protein, FGF-21 functions extracellularly, making it a key therapeutic target for metabolic disorders such as diabetes and obesity.

  • Protein name
    Fibroblast growth factor 21
  • Uniprot ID
    Q9NSA1
  • Gene Name
    FGF21
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 44-209 aa (Q9NSA1) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 19.49 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 19 kDa band.
  • Purity
    >86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"