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Product Name
Recombinant FCRL6 protein (His tag)
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Description
Recombinant Human Fc receptor-like protein 6 (FcRL6) fragment (amino acids 20-307) is a high-purity protein designed for studying the specific functions of its three Ig-like C2-type domains. This fragment serves as an essential tool for researchers investigating MHC class II receptor mechanisms in immune cell regulation.
Fc receptor-like protein 6 (FcRL6) is a human single-pass type I membrane protein localized to the cell surface. It functions as an MHC class II receptor but does not act as an Fc receptor. Unlike other Fc receptor homologs, FcRL6 does not contribute to cytokine production or cytotoxic granule release in NK cells and CD8+ T cells when stimulated independently. Its specific role in immune modulation through MHC class II interaction makes it a valuable target for immunological research and therapeutic development.
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Protein name
Fc receptor-like protein 6
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Uniprot ID
Q6DN72
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Gene Name
FCRL6; FCRH6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 20-307 aa (Q6DN72) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 33.38 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 33 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"