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Product Name
Recombinant FCGRB protein (His tag)
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Description
Recombinant human Putative High Affinity Immunoglobulin Gamma Fc Receptor IB (FCGR1BP) fragment (residues 16-198) is a 183-amino acid protein designed for studying Fc receptor interactions. This fragment encompasses the complete Ig-like C2-type 1 and C2-type 2 domains, making it an ideal tool for investigating immunoglobulin gamma binding and humoral immune response mechanisms.
The full-length Putative High Affinity Immunoglobulin Gamma Fc Receptor IB (FCGR1BP) is a single-pass type I membrane protein localized to the cell membrane. It functions as a low-affinity receptor for the Fc region of immunoglobulins gamma, potentially playing a role in humoral immune responses by mediating antibody interactions. This receptor may serve as a regulatory component in immune complex recognition and processing, though it exhibits lower binding affinity compared to FCGR1A.
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Protein name
Putative high affinity immunoglobulin gamma Fc receptor IB
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Uniprot ID
Q92637
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Gene Name
FCGR1BP; FCGR1B; IGFRB
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 16-198 aa (Q92637) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 22.44 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 22 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"