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Product Name
Recombinant FABP4 protein (His tag)
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Description
Recombinant Human FABP4 Protein (Fragment 2-132) is a high-quality, stable fragment of Fatty Acid-Binding Protein 4 (FABP4), designed for structural and biochemical studies. This fragment retains key functional regions, offering researchers a reliable tool to investigate lipid transport mechanisms in adipocytes.
Fatty Acid-Binding Protein 4 (FABP4), also known as Adipocyte Lipid-Binding Protein, is a crucial lipid transport protein in adipocytes. It binds long-chain fatty acids and retinoic acid, facilitating their delivery to nuclear receptors. The protein localizes to both the cytoplasm and nucleus, with nuclear translocation triggered by ligand binding, while being subject to constitutive nuclear export. This dynamic subcellular distribution underscores its role in lipid signaling and metabolic regulation, making it a significant target for obesity and metabolic disease research.
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Protein name
Fatty acid-binding protein, adipocyte
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Uniprot ID
P15090
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Gene Name
FABP4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 2-132 aa (P15090) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 16.24 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 17 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"