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Product Name
Recombinant ETV4 protein (His tag)
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Description
Recombinant Human ETS translocation variant 4 (ETV4) Fragment (aa 340-433) – a high-quality, stable protein fragment designed for structural and biochemical studies. This 94-amino acid fragment offers excellent solubility and is ideal for investigating the transcriptional regulatory functions of ETV4 in a manageable format.
ETV4 is a transcriptional activator involved in key cellular processes, including keratinocyte differentiation. It also plays a role in viral interactions, binding to the adenovirus E1A gene enhancer to activate transcription. The full-length protein is nuclear-localized, consistent with its function in gene regulation. This recombinant fragment provides a stable, soluble unit for focused research on ETV4's mechanisms without domain complexities.
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Protein name
ETS translocation variant 4
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Uniprot ID
P43268
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Gene Name
ETV4; E1AF; PEA3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 340-433 aa (P43268) were fused with C-terminal 6His tag.
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Sequence
MSKIKALQLW QFLVALLDDP TNAHFIAWTG RGMEFKLIEP EEVARLWGIQ KNRPAMNYDK LSRSLRYYYE KGIMQKVAGE RYVYKFVCEP EALFSLAFPL EHHHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 12.72 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 13 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant ETV4 protein (His tag) SDS-PAGE
M: Marker; Lane 1: ETV4
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"