Epinecidin-1 peptide

Epinecidin-1 peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

GFIFHIIKGLFHAGKMIHGLV-NH2

H-Gly-Phe-Ile-Phe-His-Ile-Ile-Lys-Gly-Leu-Phe-His-Ala-Gly-Lys-Met-Ile-His-Gly-Leu-Val-NH2

21

95%

C₁₁₄H₁₇₆N₃₀O₂₁S

2334.91

71312054

Synthetic

Powder

Epinecidin-1 corresponds to positions 22-42 of the grouper (Epinephelus coioides) epinecidin-1 and shows structural homology to pleurocidin found in the winter flounder (Pleuronectes americanus). The synthetic peptide Epinecidin-1 exhibits antiviral activity against non-enveloped, spherical virus (betanodavirus). In zebrafish models, Epi-1 reduces MRSA bacterial counts in wounded regions, promotes wound healing, and increases angiogenesis. The source of Epinecidin-1 is orange-spotted grouper, Epinephelus coioides.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Z.X.Yin et al., Aquaculture, 253, 204 (2006)
• C.Y.Pan et al., DNA Cell Biol., 26, 403 (2007)
• J.Y.Chen et al., Peptides, 30, 2365 (2009)
• C.Y.Pan et al., Peptides, 30, 1058 (2009)
• W.J.Lin et al., Peptides, 30, 283 (2009)
• C.Y.Pan et al., Peptides, 31, 806 (2010)
• T.J.Chia et al., Fish Shellfish Immunol., 28, 434 (2010)
• Y.D.Wang et al., Fish Shellfish Immunol., 28, 113 (2010)

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.