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Product Name
Recombinant EPHA6 protein (His tag)
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Description
Introducing the recombinant protein fragment of Ephrin type-A receptor 6 (EPHA6), encompassing amino acids 747-1036. This 290-amino acid fragment includes the SAM domain, making it an ideal tool for investigating domain-specific functions in receptor tyrosine kinase signaling pathways.
Ephrin type-A receptor 6 (EPHA6) is a receptor tyrosine kinase that promiscuously binds GPI-anchored ephrin-A family ligands on adjacent cells, facilitating contact-dependent bidirectional signaling. This interaction enables forward signaling through the receptor and reverse signaling through the ephrin ligand, mediating critical cell-cell communication processes. The full-length protein is localized to the membrane as a single-pass type I membrane protein, positioning it to participate in intercellular signaling events at cell boundaries.
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Protein name
Ephrin type-A receptor 6
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Uniprot ID
Q9UF33
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Gene Name
EPHA6; EHK2; HEK12
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 747-1036 aa (Q9UF33) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 34.70 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 35 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"