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Product Name
Recombinant EFNB3 protein (His tag)
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Description
Recombinant Human Ephrin-B3 (EFNB3) Fragment (aa 28-172) is a high-purity protein designed for studying the Ephrin RBD domain. This product supports research into neuronal development, viral entry mechanisms, and cell signaling pathways, offering a precise tool for domain-specific functional assays.
Ephrin-B3 is a transmembrane ligand that binds promiscuously to Eph receptors, facilitating bidirectional signaling critical for neuronal, vascular, and epithelial development, including roles in axon guidance and adhesion. It is also implicated as a receptor for Nipah and Hendra viruses, highlighting its importance in infectious disease research. The full-length protein is localized to the membrane as a single-pass type I membrane protein, underscoring its role in cell-cell communication.
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Protein name
Ephrin-B3
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Uniprot ID
Q15768
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Gene Name
EFNB3; EPLG8; LERK8
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 28-172 aa (Q15768) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 18.11 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 18 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"