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Product Name
Recombinant EF1A protein (His tag)
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Description
Recombinant Elongation factor 1-alpha (EF-1-alpha) fragment (residues 1-463) from Caenorhabditis elegans, encompassing the full tr-type G domain. This high-quality protein is an essential tool for investigating GTP-dependent aminoacyl-tRNA binding and ribosome interactions in protein biosynthesis studies.
Elongation factor 1-alpha (EF-1-alpha) plays a critical role in protein synthesis by promoting the GTP-dependent binding of aminoacyl-tRNA to the ribosomal A-site, ensuring accurate translation elongation. As a cytoplasmic protein in Caenororhabditis elegans, it is fundamental to cellular function and gene expression regulation. The provided fragment spans residues 1-463, fully containing the functional tr-type G domain, enabling targeted research into its specific mechanistic contributions to translation fidelity and efficiency.
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Protein name
Elongation factor 1-alpha
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Uniprot ID
P53013
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Gene Name
eef-1A.1; eef-1A.2; ;
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-463 aa (P53013) were fused with 6His tag.
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Sequence
1-463
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Protein Species
Caenorhabditis elegans
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Molecular weight
Predictes a molecular mass of 52.33 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 52 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"