DIM-LF11-318 peptide
Not For Human Use, Lab Use Only.
Cat.#: 319253
Special Price 186.90 USD
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Product Name
DIM-LF11-318 peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
H-FWQRRIRRWRRFWQRRIRRWRR-NH2
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Sequence
H-Phe-Trp-Gln-Arg-Arg-Ile-Arg-Arg-Trp-Arg-Arg-Phe-Trp-Gln-Arg-Arg-Ile-Arg-Arg-Trp-Arg-Arg-NH2
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Length (aa)
22
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Peptide Purity (HPLC)
95.45%
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Molecular Formula
C156H243N65O24
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Molecular Weight
3413.01
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Source
Synthetic
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Form
Powder
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Description
DIM-LF11-318 shows high activity against cancer cells, however as well against non-cancer cells confirming their low selectivity demonstrated by the PI uptake. The non-specific peptide DIM-LF11-318 induced a fast killing and slight swelling of the melanoma cells (SBcl-2) with visible lyses of the membrane during the PI-uptake
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- Riedl S, Leber R, Rinner B, Schaider H, Lohner K, Zweytick D. Human lactoferricin derived di-peptides deploying loop structures induce apoptosis specifically in cancer cells through targeting membranous phosphatidylserine. Biochim Biophys Acta. 2015 Nov;1848(11 Pt A):2918-31. doi: 10.1016/j.bbamem.2015.07.018. Epub 2015 Aug 1. PMID: 26239537.
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"