Dicynthaurin peptide

Dicynthaurin peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

ILQKAVLDCLKAAGSSLSKAAITAIYNKIT

Ile-Leu-Gln-Lys-Ala-Val-Leu-Asp-Cys-Leu-Lys-Ala-Ala-Gly-Ser-Ser-Leu-Ser-Lys-Ala-Ala-Ile-Thr-Ala-Ile-Tyr-Asn-Lys-Ile-Thr

30

98.1%

Synthetic

Powder

Mostly C-terminally amidated. On the weight basis, the monomer and dimer are equally active. However, the monomer is less hemolytic. Either the monomer or dimer is helical in the presence of membrane-mimetic TFE or SDS. It's speculated that the peptide may have two conformations as evidenced by the two peaks on HPLC. Updated June 2010. Dicynthaurin has Antibacterial activity. Dicynthaurin was found in Halocynthia aurantium.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Lee IH, Lee YS, Kim CH, et al. Dicynthaurin: an antimicrobial peptide from hemocytes of the solitary tunicate, Halocynthia aurantium. Biochim Biophys Acta. 2001;1527(3):141-8.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.