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  • (Des-Bromo)-Neuropeptide B (1-23) (human)

(Des-Bromo)-Neuropeptide B (1-23) (human)

Not For Human Use, Lab Use Only.

Cat.#: 313977

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Product Information

  • Product Name
    (Des-Bromo)-Neuropeptide B (1-23) (human)
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    WYKPAAGHSSYSVGRAAGLLSGL
  • Sequence
    H-Trp-Tyr-Lys-Pro-Ala-Ala-Gly-His-Ser-Ser-Tyr-Ser-Val-Gly-Arg-Ala-Ala-Gly-Leu-Leu-Ser-Gly-Leu-OH
  • Length (aa)
    23
  • Peptide Purity (HPLC)
    96.2%
  • Molecular Formula
    C107H162N30O30
  • Molecular Weight
    2348.65
  • Source
    Synthetic
  • Form
    Powder
  • Description
    (Des-Bromo)-Neuropeptide B (1-23) (human), a neuropeptide B derivative, has been shown to inhibit forskolin-induced cAMP production in CHO- cells expressing either bovine or human G-protein-coupled receptor GPR7 to a similar extent as neuropeptide B (human). The IC50 values for bovine and human GPR7 are 3.5 nM and 0.58 nM, respectively.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Fujii R, Yoshida H, Fukusumi S, et al. Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7. J Biol Chem. 2002;277(37):34010-6.
    • Fujii R, Yoshida H, Fukusumi S, et al. Identification of a neuropeptide modified with bromine as an endogenous ligand for GPR7. J Biol Chem. 2002;277(37):34010-6.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight

Peptide Property

  • Analysed Sequence:H-WYKPAAGHSSYSVGRAAGLLSGL-OH
  • Chemical Formula:C107H162N30O30
  • Sequence length:23
  • Extinction coefficient:8250 M-1cm-1
  • GRAVY:0.06
  • Mw average:2348.6
  • Theoretical pI:10.04
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"