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  • Dermaseptin-S1 peptide

Dermaseptin-S1 peptide

Not For Human Use, Lab Use Only.

Cat.#: 313474

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* Buy 1 get 1 free (?) What is TFA?

Special Price 430.10 USD

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Product Information

  • Product Name
    Dermaseptin-S1 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
  • Sequence
    Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln
  • Length (aa)
    34
  • Peptide Purity (HPLC)
    95.03%
  • Molecular Formula
    C152H257N43O44S2
  • Molecular Weight
    3455.04
  • CAS No.
    136212-91-4
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The peptide is active against Leishmania major (Perez-Cordero JJ et al. 2011 Peptides in press). Also showed spermicidal activity. A segment corresponding to residue 1-18 was found to have a comparable activity to the parent peptide (JBC 1994; 269: 1934-39). Helix in TFE. This peptide could inhibit HIV infection at a concentration that is also toxic to T cells (J Virol 2005; 79:11598-11606) Dermaseptin-S1 has Antibacterial, Antifungal activity. The source of Dermaseptin-S1 is Sauvage's leaf frog, Phyllomedusa sauvagii, South America.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Mor A, Nicolas P. Isolation and structure of novel defensive peptides from frog skin. Eur J Biochem. 1994;219(1-2):145-54.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ-OH
  • Chemical Formula:C152H257N43O44S2
  • Sequence length:34
  • Extinction coefficient:5690 M-1cm-1
  • GRAVY:0.19
  • Mw average:3455.04
  • Theoretical pI:10.55
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"