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  • Decoralin-NH2 peptide

Decoralin-NH2 peptide

For research use only. We do not sell to patients.

Cat.#: 318946

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Optional Service: TFA RemovalWhat's this?

Special Price 99.2 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Decoralin-NH2 peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    H-SLLSLIRKLIT-NH2
  • Three letter code
    H-Ser-Leu-Leu-Ser-Leu-Ile-Arg-Lys-Leu-Ile-Thr-NH2
  • Length (aa)
    11
  • Peptide Purity (HPLC)
    95.79
  • Molecular Formula
    C58H110N16O14
  • Molecular Weight
    1255.59
  • Source
    Synthetic
  • Additional Information
    These factors are present in decoralin-NH2, but not in decoralin, which as a consequence, led to the lower helical content of decoralin than decoralin-NH2. However, when comparing decoralin versus anoplin, both in the amidated form, other structural features should be taken into account for this case. These features are principally related to the average hydrophobicity and hydrophobic moment, and the angle subtended by their polar faces. Anoplin presents a lower mean hydrophobic moment and mean hydrophobicity and higher polar angle than decoralin, these parameters would contribute to its lower helical content in the zwitterionic and in anionic vesicles compared to the decoralins. Moreover, these parameters taken together can also be correlated to the enhanced biological activities of decoralin-NH2 in relation to anoplin.
  • Storage Guidelines
    Ideally Decoralin-NH2 peptide should be stored in a freezer at or below -9C. Decoralin-NH2 peptide should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Konno, Katsuhiro et al. “Decoralin, a novel linear cationic alpha-helical peptide from the venom of the solitary eumenine wasp Oreumenes decoratus.” Peptides vol. 28,12 (2007): 2320-7.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"