Decoralin peptide

Decoralin peptide

• COA/MS/HPLC Report
• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

SLLSLIRKLIT

Ser-Leu-Leu-Ser-Leu-Ile-Arg-Lys-Leu-Ile-Thr

11

95.6%

C₅₈H₁₀₉N₁₅O₁₅

1256.57

Synthetic

Powder

Active against Gram-positive S. aureus CCT 6538, S. saprophyticus, B. subtilis CCT 2471, B. thuringiensis (MIC all at 40 uM), Gram-negative E. coli ATCC 25922 (MIC 80 uM), K. pneumoniae ATCC 13883 (80 uM), and A. faecalis ATCC 8750 (MIC 40 uM), and yeast C. albicans (40 uM). It only showed weak leishmanicidal activity IC50=72 uM (cf. amidated 11 uM). Essentially not hemolytic. Helical in TFE, SDS micelles, or PC/PG (70/30) vesicles, but not in PC vesicles. Sequence validated by Dr. Jan A. Hiss. Updated 5/23/12. Decoralin has Antibacterial, Antifungal activity. Decoralin was found in venom, solitary eumenine wasp, Oreumenes decoratus.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Konno K, Rangel M, Oliveira JS, et al. Decoralin, a novel linear cationic alpha-helical peptide from the venom of the solitary eumenine wasp Oreumenes decoratus. Peptides. 2007;28(12):2320-7.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.