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  • D-K6L9 peptide

D-K6L9 peptide

Not For Human Use, Lab Use Only.

Cat.#: 319114

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* Buy 1 get 1 free (?) What is TFA?

Special Price 127.40 USD

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Product Information

  • Product Name
    D-K6L9 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-LKLLKKLLKKLLKLL-NH2, Leucines 3 and 8, and lysines 6,9 and 13 are D enantiomers
  • Sequence
    H-Leu-Lys-Leu-Leu-Lys-Lys-Leu-Leu-Lys-Lys-Leu-Leu-Lys-Leu-Leu-NH2, Leucines 3 and 8, and lysines 6,9 and 13 are D enantiomers
  • Length (aa)
    15
  • Peptide Purity (HPLC)
    99.47%
  • Molecular Formula
    C90H174N22O15
  • Molecular Weight
    1804.45
  • Source
    Synthetic
  • Form
    Powder
  • Description
    D-K6L9 is a host defense–like peptide composed of six lysines and nine leucines, modified by the inclusion of D-amino acids to improve antimicrobial activity and resistance to degradation by proteases. D-K6L9 shows antimicrobial and antibiofilm activities against Pseudomonas aeruginosa without inducing bacterial resistance.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Papo (2004) Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino Acid Peptide: membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion. Cancer Res. 64(16) 5779 PMID: 15313920
    • Papo et al (2006) Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide. Cancer Res. 66(10) 5371 PMID: 16707464
    • Ben Hur et al (2022) Antimicrobial Peptides against Multidrug-Resistant Pseudomonas aeruginosa Biofilm from Cystic Fibrosis Patients. J Med Chem. 2022 65(13) 9050 PMID: 35759644
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"