Cynomolgus LFA-3 / CD58 (His Tag) recombinant protein

Cat.#: 503677

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Product Information

  • Product Name
    Cynomolgus LFA-3 / CD58 (His Tag) recombinant protein
  • Documents
  • Description
    CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.
  • Protein name
    Uncharacterized protein
  • Protein short names
    LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3; LFA-3; RP5-1086K13.2; CD58; AG3; CD58 ANTIGEN; CD58 MOLECULE; LFA3; SURFACE GLYCOPROTEIN LFA-3
  • Uniprot ID
    F7HQR6
  • Gene Name
    ANGPTL7
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the cynomolgus CD58 (F7HQR6) (Met1-Arg215) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Cynomolgus
  • Molecular weight
    The recombinant cynomolgus CD58 comprises 198 amino acids and has a calculated molecular mass of 23 KDa. The apparent molecular mass of it is approximately 38-42 KDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized Cynomolgus CD58-His at 10 μg/ml (100 μl/well) can bind Cynomolgus CD2-Fc (Cat:501615), The EC50 of Cynomolgus CD2-Fc (Cat:501615) is 0.06-0.14 μg/ml.
  • Validations

    Cynomolgus LFA-3 / CD58 Protein (His Tag) SDS-PAGE

    Cynomolgus LFA-3 / CD58 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"