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Product Name
Cynomolgus IL20RB (His Tag) recombinant protein
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Description
IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.
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Protein short names
IL-20RB; IL-20 RECEPTOR SUBUNIT BETA; IL-20R-BETA; FIBRONECTIN TYPE III DOMAIN CONTAINING 6; IL20R2; MGC130209; AV228068; IL-20R2; FNDC6; HCG_2022374; INTERLEUKIN-20 RECEPTOR SUBUNIT BETA; GM186; INTERLEUKIN-20 RECEPTOR II; MGC34923; DIRS1
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Uniprot ID
G7MJP8
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the cynomolgus IL20RB (XP_005545913.1) (Asp30-Ala230) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Cynomolgus
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Molecular weight
The recombinant cynomolgus IL20RB consists of 212 amino acids and predicts a molecular mass of 23.9 kDa.
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Purity
> (77.9+15.9) % as determined by SDS-PAGE.
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Validations
Cynomolgus IL20RB Protein (His Tag)
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