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  • Cyclo(his-pro) peptide

Cyclo(his-pro) peptide

Not For Human Use, Lab Use Only.

Cat.#: 319545

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* Buy 1 get 1 free (?) What is TFA?

Special Price 144.20 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Cyclo(his-pro) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    cyclo(HP)
  • Sequence
    cyclo(-His-Pro)
  • Length (aa)
    2
  • Peptide Purity (HPLC)
    95.19%
  • Molecular Formula
    C11H14N4O2
  • Molecular Weight
    234.27
  • Source
    Synthetic
  • Form
    Powder
  • Description
    Cyclo(his-pro) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Banks WA, Kastin AJ, Akerstrom V, Jaspan JB. Radioactively iodinated cyclo(His-Pro) crosses the blood-brain barrier and reverses ethanol-induced narcosis. Am J Physiol. 1993 May;264(5 Pt 1):E723-9. doi: 10.1152/ajpendo.1993.264.5.E723. PMID: 8498494.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"