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  • cyclo-(D-Trp-Tyr) peptide

cyclo-(D-Trp-Tyr) peptide

Not For Human Use, Lab Use Only.

Cat.#: 318751

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* Buy 1 get 1 free (?) What is TFA?

Special Price 108.90 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    cyclo-(D-Trp-Tyr) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Cyclo-(D-Trp-Tyr)
  • Sequence
    Cyclo-(D-Trp-Tyr)
  • Length (aa)
    2
  • Peptide Purity (HPLC)
    95%
  • Molecular Formula
    C20H19N3O3
  • Molecular Weight
    349.39
  • Source
    Synthetic
  • Form
    Powder
  • Description
    The cyclo-(d-Trp-Tyr) peptide nanotubes (PNTs) self-associated at concentrations above 0.01 mg/mL. cyclo-(d-Trp-Tyr) PNTs could be used as an oral gene delivery carrier. The results showed that PNTs and genes could distribute to duodenum, stomach, liver and kidney after the first oral PNTs. PNTs complexed with anti-apoptotic plasmid caspase 3 silencing shRNA eye drop delivery decreased 41% of caspase 3 activity after the first dose by caspase 3 activity and Western blot analysis.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Hsieh, W. H., Chang, S. F., Chen, H. M., Chen, J. H., & Liaw, J. (2012). Oral gene delivery with cyclo -(d -Trp-Tyr) peptide nanotubes. Molecular Pharmaceutics, 9(5), 1231-1249. https://doi.org/10.1021/mp200523n
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"