CRGDK peptide
Not For Human Use, Lab Use Only.
Cat.#: 319464
Special Price 94.20 USD
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Product Name
CRGDK peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
H-CRGDK-OH
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Sequence
H-Cys-Arg-Gly-Asp-Lys-OH
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Length (aa)
5
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Peptide Purity (HPLC)
95.41%
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Molecular Formula
C21H39N9O8S
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Molecular Weight
577.65
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Source
Synthetic
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Form
Powder
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Description
CRGDK is a peptide that interacts specifically with Nrp-1. CRGDK peptide can significantly improve the cellular uptake of the PAMAM vehicle.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- Wei, T.; Liu, J.; Ma, H.; Cheng, Q.; Huang, Y.; Zhao, J.; Huo, S.; Xue, X.; Liang, Z.; Liang, X. J. Functionalized Nanoscale Micelles Improve Drug Delivery for Cancer Therapy in Vitro and in Vivo. Nano Lett. 2013, 13, 2528- 2534, DOI: 10.1021/nl400586t
- Liu D, Wang C, Yang J, An Y, Yang R, Teng G. CRGDK-Functionalized PAMAM-Based Drug-Delivery System with High Permeability. ACS Omega. 2020 Apr 14;5(16):9316-9323. doi: 10.1021/acsomega.0c00202. PMID: 32363282; PMCID: PMC7191571.
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"