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  • CPP-Morn3 (222-237) peptide

CPP-Morn3 (222-237) peptide

Not For Human Use, Lab Use Only.

Cat.#: 318737

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* Buy 1 get 1 free (?) What is TFA?

Special Price 233.90 USD

Availability: 3 weeks
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Product Information

  • Product Name
    CPP-Morn3 (222-237) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-YGRKKRRQRRRPDGVLAEALAMFRKTE-OH
  • Sequence
    H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Asp-Gly-Val-Leu-Ala-Glu-Ala-Leu-Ala-Met-Phe-Arg-Lys-Thr-Glu-OH
  • Length (aa)
    27
  • Peptide Purity (HPLC)
    95.2%
  • Molecular Formula
    C141H242N52O37S
  • Molecular Weight
    3289.81
  • Source
    Synthetic
  • Form
    Powder
  • Description

    A designed peptide that regulates two types of post-translational modifications of p53 with anti-cancer effect, based on the identification of a Morn3-mediated protein complex that confers composite modifications on p53. The findings highlight a strategy for targeting composite protein modifications with one molecule.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Liang, L., Wang, H., Shi, H., Li, Z., Yao, H., Bu, Z., u2026 Xu, J. (2018). A Designed Peptide Targets Two Types of Modifications of p53 with Anti-cancer Activity. Cell Chemical Biology, 25(6), 761u2013774.e5. doi:10.1016/j.chembiol.2018.03.010
    • Tan, J., Cheong, H., Park, Y.S., Kim, H., Zhang, M., Moon, C., and Huang, Y. (2014).Cell-penetrating peptide-mediated topical delivery of bio-macromolecular drugs. Curr. Pharm. Biotechnol. 15, 231u2013239.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight

Peptide Property

  • Analysed Sequence:H-YGRKKRRQRRRPDGVLAEALAMFRKTE-OH
  • Chemical Formula:C141H242N52O37S
  • Sequence length:27
  • Extinction coefficient:1280 M-1cm-1
  • GRAVY:-1.47
  • Mw average:3289.81
  • Theoretical pI:12.03
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"