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Product Name
Recombinant CMA1 protein (His tag)
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Description
This product is a recombinant fragment of human Chymase (EC 3.4.21.39), encompassing amino acids 22-247. It includes the complete Peptidase S1 domain, making it an ideal tool for investigating the protease's specific roles in vasoactive peptide processing, extracellular matrix remodeling, and secretory regulation.
Chymase, encoded by the CMA1 gene, is the major secreted protease of mast cells. It is primarily localized to mast cell granules and is secreted upon activation. Based on its function summary, Chymase is implicated in generating vasoactive peptides, degrading extracellular matrix components, and regulating gland secretion, highlighting its significance in inflammatory responses, tissue remodeling, and secretory processes.
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Protein name
Chymase
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Uniprot ID
P23946
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Gene Name
CMA1; CYH; CYM
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 22-247 aa (P23946) were fused with 6His tag.
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Sequence
22-247
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 26.68 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 27 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"