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Product Name
Recombinant CLCF1 protein (His tag)
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Description
Recombinant Human Cardiotrophin-like Cytokine Factor 1 (CLCF1) Fragment (35-225) is a 191-amino acid protein fragment engineered for stability and solubility, ideal for investigating neuronal development, B-cell stimulation, and cytokine signaling pathways in research applications.
Cardiotrophin-like Cytokine Factor 1 (CLCF1), also known as B-cell-stimulating factor 3 (BSF-3) or Novel Neurotrophin-1 (NNT-1), is a secreted protein that forms a heterodimeric complex with CRLF1. This complex functions as a neurotropic cytokine critical for neuronal development and additionally stimulates B-cells. CLCF1 binds to and activates the ILST/gp130 receptor, playing a key role in cytokine-mediated signaling. The protein is naturally secreted in humans, underscoring its relevance in extracellular signaling and immune-neural interactions.
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Protein name
Cardiotrophin-like cytokine factor 1
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Uniprot ID
Q9UBD9
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Gene Name
CLCF1; BSF3; CLC; NNT1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 35-225 aa (Q9UBD9) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 23.17 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23 kDa band.
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Purity
>89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"