Recombinant CLCF1 protein (His tag)

Recombinant CLCF1 protein (His tag)

Cat.#: 546154

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Product Information

  • Product Name
    Recombinant CLCF1 protein (His tag)
  • Documents
  • Description

    Recombinant Human Cardiotrophin-like Cytokine Factor 1 (CLCF1) Fragment (35-225) is a 191-amino acid protein fragment engineered for stability and solubility, ideal for investigating neuronal development, B-cell stimulation, and cytokine signaling pathways in research applications.

    Cardiotrophin-like Cytokine Factor 1 (CLCF1), also known as B-cell-stimulating factor 3 (BSF-3) or Novel Neurotrophin-1 (NNT-1), is a secreted protein that forms a heterodimeric complex with CRLF1. This complex functions as a neurotropic cytokine critical for neuronal development and additionally stimulates B-cells. CLCF1 binds to and activates the ILST/gp130 receptor, playing a key role in cytokine-mediated signaling. The protein is naturally secreted in humans, underscoring its relevance in extracellular signaling and immune-neural interactions.

  • Protein name
    Cardiotrophin-like cytokine factor 1
  • Uniprot ID
    Q9UBD9
  • Gene Name
    CLCF1; BSF3; CLC; NNT1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 35-225 aa (Q9UBD9) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 23.17 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23 kDa band.
  • Purity
    >89%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"