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Product Name
Recombinant CH3L2 protein (His tag)
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Description
Recombinant Human Chitinase-3-like protein 2 (YKL-39) Fragment (aa 27-390) is a high-purity protein designed for functional studies. This fragment fully encompasses the GH18 domains, making it an ideal tool for investigating glycan-binding interactions without chitinase activity, supporting research in cellular communication and extracellular matrix processes.
Chitinase-3-like protein 2, also known as YKL-39, is a secreted lectin that binds chitooligosaccharides and other glycans with high affinity but lacks chitinase activity. It does not bind heparin, indicating specificity in its carbohydrate recognition. As a secreted protein, it functions extracellularly, potentially involved in cell-matrix interactions or immune modulation, based on its lectin properties and localization.
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Protein name
Chitinase-3-like protein 2
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Uniprot ID
Q15782
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Gene Name
CHI3L2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 27-390 aa (Q15782) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 42.53 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 43 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"