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Product Name
Recombinant CECR2 protein (His tag)
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Description
Recombinant Human CECR2 (Cat eye syndrome critical region protein 2) Fragment (1-170 aa) is a high-quality, soluble protein designed for chromatin remodeling and histone interaction studies. This fragment provides a stable and functional unit ideal for biochemical assays, structural analysis, and epigenetic research.
CECR2 is a regulatory subunit of ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which organize nucleosome arrays to facilitate DNA replication, transcription, and repair. It recognizes and binds acylated histones (acetylated/butyrylated) and is essential for neural tube closure, inner ear development, and spermatogenesis. CECR2 localizes to the nucleus and may integrate cytoskeletal networks with vesicular trafficking and chromosome remodeling through interactions with LRPPRC.
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Protein name
Chromatin remodeling regulator CECR2
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Uniprot ID
Q9BXF3
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Gene Name
CECR2; KIAA1740
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-170 aa (Q9BXF3) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 21.48 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 25 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"