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Product Name
Recombinant CD2 protein (His tag)
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Description
Recombinant Human CD2 Fragment (aa 25-209) is a high-purity protein encompassing the Ig-like V-type and C2-type domains, essential for studying T-cell adhesion and signaling mechanisms. This fragment serves as an ideal tool for investigating specific domain functions in immune cell interactions.
CD2, or T-cell surface antigen CD2, is a single-pass type I membrane protein located on the cell surface. It mediates adhesion between T-cells and other cell types by interacting with ligands such as lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1. This interaction is critical for T-cell triggering and signaling, with the cytoplasmic domain playing a key role in signal transduction, making CD2 a significant protein in immune response research.
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Protein name
T-cell surface antigen CD2
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Uniprot ID
P06729
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Gene Name
CD2; SRBC
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 25-209 aa (P06729) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 22.91 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 25 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"