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Recombinant CC106 protein (His tag)

Recombinant CC106 protein (His tag)

Cat.#: 543524

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Product Information

  • Product Name
    Recombinant CC106 protein (His tag)
  • Documents
  • Description

    Recombinant Human Coiled-coil domain-containing protein 106 (CCDC106) fragment (aa 175-280) - a stable, soluble protein unit ideal for structural studies and functional analysis of p53/TP53 regulation.

    Coiled-coil domain-containing protein 106 (CCDC106) is a human protein that promotes the degradation of the critical tumor suppressor p53/TP53 and inhibits its transcriptional activity. This regulatory function positions CCDC106 as an important player in cellular processes involving p53-mediated pathways. The protein is localized to the nucleus where it colocalizes with p53/TP53, suggesting direct interaction and functional relationship within the nuclear compartment. The selected fragment (amino acids 175-280) represents a structurally stable region of the protein suitable for detailed biochemical characterization.

  • Protein name
    Coiled-coil domain-containing protein 106
  • Uniprot ID
    Q9BWC9
  • Gene Name
    CCDC106
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    DNA encoding 175-280 aa (Q9BWC9) were fused with 6His tag.
  • Protein Species
    Human
  • Molecular weight
    Predictes a molecular mass of 13.96 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 14 kDa band.
  • Purity
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • Activity
    Not tested.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"