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Product Name
Recombinant CBG protein (His tag)
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Description
Recombinant Human Corticosteroid-binding globulin (CBG) fragment (Serpin A6, Transcortin), encompassing residues 35-405, is a high-quality protein designed for structural and biochemical studies. This 371-amino acid fragment retains key functional characteristics and offers excellent stability and solubility, making it ideal for research on glucocorticoid and progestin transport mechanisms.
Corticosteroid-binding globulin (CBG), also known as Serpin A6 or Transcortin, is the primary transport protein for glucocorticoids and progestins in the blood across nearly all vertebrate species. It plays a critical role in regulating the bioavailability and distribution of these steroid hormones. The full-length protein is secreted into the extracellular space, where it functions in systemic hormone transport. This recombinant fragment provides a reliable tool for investigating CBG's binding properties and structural features without the complexities of the full-length protein.
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Protein name
Corticosteroid-binding globulin
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Uniprot ID
P08185
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Gene Name
SERPINA6; CBG
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 35-405 aa (P08185) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 42.99 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 43 kDa band.
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Purity
>87%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"