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Product Name
Recombinant CAZA3 protein (His tag)
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Description
Recombinant human F-actin-capping protein subunit alpha-3 (CapZ alpha-3) fragment (residues 1-299) is a high-purity protein designed for structural and biochemical studies. This fragment represents a stable, soluble unit ideal for investigating actin filament capping mechanisms in germ cell development.
F-actin-capping protein subunit alpha-3 binds to the barbed ends of actin filaments in a calcium-independent manner, regulating actin dynamics by blocking subunit exchange without severing filaments. It is localized to the cytoskeleton and plays a crucial role in spermatid morphogenesis, contributing to germ cell-specific structural organization during development.
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Protein name
F-actin-capping protein subunit alpha-3
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Uniprot ID
Q96KX2
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Gene Name
CAPZA3; CAPAA3; GSG3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-299 aa (Q96KX2) were fused with 6His tag.
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Sequence
1-299
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 36.68 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 37 kDa band.
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Purity
>88%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"