cAMP-Dependent Protein Kinase Inhibitor-alpha (5-24) (human, mouse, rabbit, rat) peptide
Not For Human Use, Lab Use Only.
Cat.#: 306007
Special Price 253.00 USD
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Product Name
cAMP-Dependent Protein Kinase Inhibitor-alpha (5-24) (human, mouse, rabbit, rat) peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
TTYADFIASGRTGRRNAIHD
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Sequence
H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
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Length (aa)
20
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Peptide Purity (HPLC)
97.7%
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Molecular Formula
C94H148N32O31
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Molecular Weight
2222.41
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CAS No.
99534-03-9
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Source
Synthetic
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Form
Powder
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Description
This 20-residue peptide represents the active site of the cAMP-dependent protein kinase inhibitor protein in skeletal muscle. It binds to the protein kinase with high affinity and inhibits this enzyme competitively.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- H.-C.Cheng et al., J. Biol. Chem., 261, 989 (1986)
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Peptide Property
- Analysed Sequence:H-TTYADFIASGRTGRRNAIHD-OH
- Chemical Formula:C94H148N32O31
- Sequence length:20
- Extinction coefficient:1280 M-1cm-1
- GRAVY:-0.75
- Mw average:2222.36
- Theoretical pI:9.84
- Data Source:Peptide Property Calculator
GRAVY = grand average of hydropathy
X: Hydrophobic uncharged residues, like F I L M V W A and P
X: Basic residues, like R K H
X: Acidic residues, like D E
X: Polar uncharged residues, like G S T C N Q and Y
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"