C-Peptide 1 (rat)
Not For Human Use, Lab Use Only.
Cat.#: 305166
Special Price 392.20 USD
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Product Name
C-Peptide 1 (rat)
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Documents
Batch to batch variation of the purity
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Sequence Shortening
EVEDPQVPQLELGGGPEAGDLQTLALEVARQ
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Sequence
H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH
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Length (aa)
31
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Peptide Purity (HPLC)
97.7%
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Molecular Formula
C140H228N38O51
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Molecular Weight
3259.58
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CAS No.
41475-27-8
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Source
Synthetic
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Form
Powder
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Description
Studies of the cellular effects of C-peptide have shown that it binds specifically in a nanomolar concentration range to a G-protein coupled membrane receptor, with subsequent activation of Ca2+-dependent intracellular signaling pathways. This resulted in stimulation of both Na+-K+-ATPase, and endothelial nitric oxide synthase activities. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body g
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- H.S.Tager and D.F.Steiner, J. Biol. Chem., 247, 7936 (1972)
- J.Markussen and F.Sundby, Eur. J. Biochem., 25, 153 (1972)
- J.Wahren et al., Am. J. Physiol. Endocrinol. Metab., 278, E-759 (2000)
- Y.Sato et al., Cell. Mol. Life Sci., 61, 727 (2004)
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About TFA salt
Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.
Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.
Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.
In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Peptide Property
- Analysed Sequence:H-EVEDPQVPQLELGGGPEAGDLQTLALEVARQ-OH
- Chemical Formula:C140H228N38O51
- Sequence length:31
- Extinction coefficient:0 M-1cm-1
- GRAVY:-0.42
- Mw average:3259.51
- Theoretical pI:3.38
- Data Source:Peptide Property Calculator
GRAVY = grand average of hydropathy
X: Hydrophobic uncharged residues, like F I L M V W A and P
X: Basic residues, like R K H
X: Acidic residues, like D E
X: Polar uncharged residues, like G S T C N Q and Y
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"