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Product Name
Recombinant BUD31 protein (His tag)
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Description
Recombinant Human BUD31 Protein Fragment (1-144) - A highly stable and soluble fragment of Protein BUD31 homolog, specifically designed for structural and biochemical studies of pre-mRNA splicing mechanisms and androgen receptor transcriptional regulation.
The full-length Protein BUD31 homolog (also known as EDG-2 or G10 homolog) is a nuclear protein involved in the pre-mRNA splicing process, playing a crucial role in mRNA processing and maturation. Research indicates its localization in chromatin at the promoter regions of androgen receptor (AR) target genes, where it functions as a regulator that may enhance AR transcriptional activity. This nuclear protein's involvement in both splicing regulation and transcriptional control makes it an important target for studying gene expression mechanisms and nuclear processes in human cells.
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Protein name
Protein BUD31 homolog
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Uniprot ID
P41223
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Gene Name
BUD31; EDG2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-144 aa (P41223) were fused with 6His tag.
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 18.65 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 19 kDa band.
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Purity
>86%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"